INCIDENCE OF NONHEMOLYTIC TRANSFUSION REACTION DUE TO IMMUNOLOGICAL REACTIONS

Febrile nonhemolytic transfusion reactions.

A. FNHTRs are reported in 0.5%–5% of all transfusions. B. FNHTRs are the most common complication of platelet transfusion. 1. Incidence ranges from 1.7% to 31%. 2. Higher incidences are seen in patients who have received multiple prior transfusions. C. Incidence may decrease with increased use of prestorage leukocytereduced blood products. D. Higher incidence of blood transfusion reactions occu...

Universal leukoreduction decreases the incidence of febrile nonhemolytic transfusion reactions to RBCs.

BACKGROUND Febrile nonhemolytic transfusion reactions (FNHTR) is a relatively common complication associated with allogeneic transfusion. Because WBCs have been implicated in the mechanism of FNHTRs, it has been proposed that the transfusion of leukoreduced RBCs should be associated with a decreased incidence of FNHTRs. These reactions are generally not life threatening, but they are expensive ...

Hemolytic transfusion reaction due to anti-A.

Hemolytic transfusion reaction due to anti-IH.

BACKGROUND Anti-IH is usually a clinically insignificant antibody that may complicate a serologic workup. However, it can occasionally cause hemolysis. We report a rare case of acute hemolysis caused by anti-IH. CASE REPORT A 60-year-old man with a long history of chronic myelomonocytic leukemia and anemia, blood group A, D+ was found to have an unidentified antibody on serologic workup. He r...

Transfusion reactions due to plasma incompatibility in dogs.

Plasma incompatibility was investigated as a possible factor in transfusion reactions in dogs. Urticaria, failure to retain within the circulation the equivalent of transfused plasma volume and protein, and increased gastric acid secretion almost invariably followed transfusion of plasma from another dog but not transfusion of the dog's own plasma. The cutaneous reactions were abolished and the...